• Active Ingredient:

    Sildenafil and Tadalafil
  • Expiry Date:

  • Manufacturer:

  • Average Delivery Time:

    25 days
  • Availability:

    In Stock
  • Strength: 120 mg

  • Rate Per Pill

    $ 1.48

Sildalis - The Perfect Combo to combat Male ED


Sildalis (Sildenafil and Tadalafil) is a medication suggested for treating Erectile Dysfunction in men (also called ‘Male Impotence’). This medicinal remedy is developed using two highly competent and proven ingredients called Sildenafil Citrate and Tadalafil. Both of these ingredients are prominent anti-ED medicine. Sildalis is an alleviative drug providing instant effect against Male Impotence. It is a Phosphodiesterase-5 inhibitor, which can restore penile erectile functioning through its sophisticated action mechanism. Sildalis tablets are generally red film coated pills. Each tablet contains 100mg of Sildenafil and 20mg of Tadalafil.


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Action Mechanism

Time it takes to start working: You can see the results after 30-45 minutes post intaking the pill.

This medicine can counteract PDE-5 enzyme, which is Type-5 of Phosphodiesterase enzyme that hinders mechanism of penile erection by undermining cyclic Guanosine Monophosphate (cGMP). Sildalis through Sildenafil and Tadalafil counteracts PDE-5 (without affecting other Phosphodiesterase types). This prevents degradation of cGMP level, which is essential for normal penile erection mechanism. Cyclic Guanosine Monophosphate responds to Nitric Oxide (NO) release and relaxes muscles in the penile area. It also simultaneously dilates crucial penile blood vessels such as dorsal arteries, helicine arteries, etc., in order to allow unobstructed blood flow into the reproductive organ. Enhanced blood supply to the organ results in hyperaemic engorgement of the reproductive organ rendering it suitable for intercourse.

Effect lasting: The effects of drug last for around four to six hours.


  • Each tablet contains 100 mg Sildenafil Citrate and 20 mg Tadalafil. This is suitable for impotent men.
  • Older men and medically unfit individuals may need adjustments with the dosage and a doctor can best do this.
  • The doctor might suggest dosage adjustments after looking at several factors such as underlying medical conditions, medical history, tolerance level and age.
  • Dosage administration is restricted to one tablet, if at all necessary to be used on daily basis. If you take more than one pill in a span of 24 hours, chances of side effects increase.
  • The tablet should not be chewed, crushed or broken before it is imbibed; it should be taken as whole with glass of water.
  • It can be taken on empty stomach or with food, but one should avoid heavy meal as it may abate the effects of the medicine.
  • Only one tablet of the drug should be consumed preferably 20 minutes to an hour before indulging in act of sexual intimacy.


  • Sildalis can cause side effects such as drowsiness and unstable attention. This may be harmful while performing tasks that demand for alertness such as driving, riding, etc. Hence, avoid such activities after taking the medicine.
  • Remember that the medicine does not protect you from HIV or STDs. It is also not a medicine to prevent pregnancy.
  • Do not use Sildalis if you are using other medicines including other PDE-5 inhibitors. You can always speak with a doctor and seek contraindication knowledge.
  • Do not allow children, women and pregnant females to take this medicine, as it may cause unwanted complications.
  • Individuals with liver, kidney or lung issues are suggested to consult their doctor before buying the medicine and determine whether it is safe for use.

Side Effects

There are mild to moderate and severe side effects of taking Sildalis.

Some of common and mild side effects include:

  • Blur sight
  • Headache
  • Drowsiness or dizziness
  • Nasal congestion
  • Dyspepsia or upset stomach
  • Body pain
  • Queasiness and vomiting
  • Diarrhea

Serious side effects include:

  • Breathing problem
  • Increased blood pressure
  • Priapism (abnormally prolonged erection)
  • Seizures
  • Irregular heartbeats
  • Swelling in feet or hands
  • Chest pain or feeling of fullness
  • Hearing loss or Tinnitus like symptoms

These symptoms may range from mild to severe. It is wise to consult your doctor if any health irregularity is experienced.


  • Sildalis should be avoided if you are sensitive to any of its ingredient, including Sildenafil and Tadalafil.
  • This medicine is not suggested for people with blood pressure issues, chest issues, etc.
  • Combination of Sildenafil and Tadalafil may react with nitrate; thus, avoid any product that contains nitrate (any form), if you are using anti- ED medicines.
  • Grape (any grape product) can increase Sildenafil level in the body fortifying its effect to harmful level.
  • The medicine should not be used in combination of ethanol, as it may increase the effect of medicine leading to severe side effects
  • Alcohol can also lead to reactions such as lowered blood pressure, if used in combination with the drug.
  • There are certain chemical ingredients that may react with Sildalis and these include bosentan, nefazodone, cimetidine, itraconazole, etc. It may also react with drugs prescribed for HIV/AIDS, heart issues blood pressure, hepatitis-C, tuberculosis, convulsions, antifungal medicines, etc.


What is Sildalis?

Sildalis is a combination of sildenafil and tadalafil, the most well-known drugs for erectile dysfunction (ED). It is an effective, modern medicine to improve your ability to get and sustain an erection. It increases your confidence in your ability to get and maintain an erection and helps you have satisfied sexual intercourse. Sildalis is a combination of both Viagra and Cialis so it is effective for men with a severe degree of erectile dysfunction.

What is the difference between Sildalis, Viagra, and Cialis?

Sildalis is actively composed of sildenafil (Viagra) and tadalafil (Cialis). It is a generic medicine equivalent to Viagra and Cialis, which is available at a much lower cost. Sildalis has demonstrated that it is medically identical to Viagra and Cialis. This generic combination of sildenafil and tadalafil costs you less than a dollar per pill, while Viagra and Cialis cost you more than $50 each pill.

How to take Sildalis pills?

The recommended dose for Sildalis is one tablet taken one hour before sexual activity. Swallow the whole pill with a glass of water, preferably on an empty stomach. You can take it with or without food. Taking the medicine with a fat-rich meal could affect the drug’s absorption, delaying its effects. You should not take this medicine more than once a day. Overdosing with this medicine could increase the risk of experiencing side effects.

How long do Sildalis pills last?

You can expect Sildalis to last for approximately 36 hours. You must be sexually aroused for this ED treatment to work. Though the drug will stay in the body for 36 hours, you will not have an erection for that period.  Sildalis takes about 30 to 60 minutes to take effect. Doctors recommend taking this medicine on an empty stomach. They also advise avoiding alcohol and grapefruits while taking this medicine.

Can I take Sildalis with other medicines?

There are some medicines, which should not be taken when you are about to take Sildalis. They include drugs used to treat prostate problems, chest pain (angina), seizures, pulmonary hypertension, and HIV. It is dangerous to take this medicine with nitrates, alpha-blockers, riociguat, protease inhibitors, certain antimicrobial drugs, and other PDE5 inhibitors. You also cannot drink alcohol with this strong ED medicine.

Why if Sildalis does not work for me?

If Sildalis is not effective, it could be because you might have taken it with a large meal. Doctors recommend taking a Sildalis pill with water on an empty stomach, one hour before sexual activity. For Sildalis to work, you must still be sexually aroused; if not, you will not get an erection. For first time users, if the drug fails to work, try it at least 8 to 10 times on separate occasions.

Where can I buy Sildalis?

You can buy Sildalis online from MedExpressRx. However, you have to provide a prescription before placing an order. Ordering this generic medicine using MedExpressRx is completely confidential and takes only a few minutes. The store ensures all customers save money on their generic drugs.

Customer's Review

Average Rating : 4 / 5

  • Sildalis has worked for me very well to treat Erectile Dysfunction. It is made by combining two powerful drugs Sildenafil and Tadalis. It is a palliative drug that works quickly within 45 minutes and helps to attain an erection. MedExpressRx provides it at an affordable price.

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