A-Ret Gel 0.1% contains Tretinoin as an active component, which is a derivative of Vitamin A that works to treat acne on your skin. This cream is applied topically on your skin. It is useful for acne and sun-damaged skin. The active drug may irritate at the start, but it works for the regeneration of new cells in your skin rapidly. To get the benefit, use A-Ret Gel 0.1% regularly. It works to prevent acne for a prolonged period. The A-Ret Gel 0.1% also works to reduce wrinkles, darkened skin patches (hyperpigmentation), and uneven areas of skin. These issues arise because of sun damage.