Difference Between Tadalafil, Sildenafil, And Vardenafil

By Jason GrayJan 01, 2021197

Difference Between Tadalafil, Sildenafil, And Vardenafil

Erectile Dysfunction (ED) is a typical sexual ailment in men. Around; 30 million men are suffering erectile dysfunction in the USA. Men with ED cannot last longer during sexual activity, which leaves both parties in an unsatisfactory state. So, if you have erectile dysfunction, you need to take help and seek treatment. Treatment choices for ED involve mental, lifestyle, and medical therapies. Medications to treat erectile dysfunction are commonly advised, such as tadalafil, sildenafil, and vardenafil. These three are generic medicines that are in great demand in the market.

These generic medicines are available over a prescription at different trustworthy online pharmacies. These all medicines are phosphodiesterase-5 (PDE5) inhibitor drugs, and they work by improving blood augmentation to the male reproductive organ. These medications serve a man to get and sustain an erection. These medicines are used when required.

How do Tadalafil, sildenafil, and vardenafil drugs act?

Tadalafil, sildenafil, and vardenafil are PDE5 inhibitor drugs. They are used as one of the primary treatments against ED. Cialis is the trade name for tadalafil, Viagra is the trade name for the drug sildenafil, and Levitra is the trade name for vardenafil. All these medicines work in a similar way to combat erectile dysfunction. They are all PDE5 inhibitors.

These pills act efficiently to inhibit the PDE5 enzyme. This enzyme is responsible for blocking blood flow to the male organ. Therefore, inhibiting this enzyme stimulates the secretion of cGMP and nitric oxide. They help enhance blood flow to the penile organ by relaxing the muscles and dilating the blood vessels. Finally, the enhanced blood flow results in an erection. However, to attain an erection sexual stimulation is essential. The onset action time of PDE5 inhibitor drugs is within 30 to 60 minutes. 

Why men prefer buying tadalafil, sildenafil, and vardenafil?

Instead of branded anti-impotent medicines, men prefer generic drugs. The generic versions provide the same results as the branded drugs, but they are available at the lowest price than the branded drugs. Availability of tadalafil, sildenafil, and vardenafil generic drugs is higher in the market. Therefore, men usually prefer buying generic anti-impotent pills. Various online pharmacies nowadays provide generic ED medicines. These generic counterparts are the same as the branded versions; however, they might differ in packaging, brand name, color, and shape. 

How to use PDE5 inhibitor drugs?

The dosage of tadalafil, sildenafil, and vardenafil pills is similar. One needs to take one of these medicines once when needed. Take either of these pills when you want to indulge in sexual activity with your partner. Take one tablet an hour before indulging in lovemaking. Just take one dosage in 24 hours. Men dealing with severe health issues should take this drug after consulting their health professional to avoid dangerous side effects.

Common side effects of tadalafil, sildenafil, and vardenafil

  • Headache
  • Indigestion
  • Flushing
  • Nasal congestion
  • Runny nose 
  • Sleepiness
  • Dizziness

Difference between Tadalafil, Sildenafil, and Vardenafil

Now we know that these drugs do not have significant differences. However, all three medicines i.e. tadalafil, sildenafil, and vardenafil differ, concerning how long their effect lasts. It is the crucial difference in all three medications.

Sildenafil is the drug that men use when they desire sexual activity. A person takes a sildenafil tablet 30 minutes to 1 hour before sexual activity, and its effects typically last up to 4 to 5 hours.

Vardenafil may start working rapidly than sildenafil citrate. However, its effect also lasts up to 4 to 5 hours.

Tadalafil is the only anti-impotent drug, which provides 36 hour-effect. For this reason, numerous men opt for tadalafil over sildenafil and vardenafil drugs.

Standard dosages of tadalafil, sildenafil, and vardenafil

Tadalafil, sildenafil, and vardenafil PDE5 inhibitor drugs differ concerning their ideal standard dosage. These medicines are available in different potencies, but their lowest standard dosages are different. Below mentioned are their ideal standard dosages:

  • Sildenafil 100mg
  • Tadalafil 20mg
  • Vardenafil 10mg

One must take these dosages under medical supervision. You need to figure out which drug will be suitable for your health because the dosage depends on the severity of the condition and your medical history.

Which medicine is most effective against erectile dysfunction?

Compared to placebo all three generic drugs i.e. tadalafil, sildenafil, and vardenafil are highly effective for treating erectile dysfunction. Most of the differences between these three medicines have to do with how long the drug lasts, how it is taken, the medical history of the person taking it, and their standard dosages. 

However, all the medicines are efficacious to control weak erections, but tadalafil is preferred over the other two drugs as it is also used for treating Benign prostatic hyperplasia (BPH). Vardenafil and Viagra are preferred because of their short effect. It is suitable for those who do not use anti-impotent pills on regular basis.

Cost and availability differences 

Another most important thing; a person might consider while buying any one of these three drugs is cost and availability. Even though tadalafil is a popular choice to treat ED, sildenafil citrate availability is higher than others. It is because sildenafil citrate holds the largest markets till today. It has gained the trust of customers across the globe in two decades. Therefore, no doubt, sildenafil citrate demand is higher than any other anti-impotent tablets. 

The generic versions of tadalafil, sildenafil, and vardenafil have approval from the FDA. Thus, they are easily available at the lowest price.

Viagra (sildenafil): Viagra anti-impotent drug is available since 1998 and is possibly one of the best anti-impotent medicines for ED in the world. Its use in the USA is extensive, and numerous pharmacies sell it.

Cialis (tadalafil): Cialis is available in the market since 2003. It is broadly available, and it might be available at the lowest price than Viagra.

Levitra (vardenafil): Levitra got FDA approval in 2003 and is available in most drugstores in the USA. There is a generic version, but it is not as popular as tadalafil or sildenafil.

So these were the differences and similarities between tadalafil, sildenafil, and vardenafil anti-impotent medicines in brief. One can choose any one of these drugs to treat erectile dysfunction. They provide the same desired effect. Remember to learn about the warnings, precautions, and contraindications of tadalafil, sildenafil, and vardenafil drugs. So, you can safely use them to beat weak erections. You can check several trusted online pharmacies in the USA to buy these generic medicines. These medicines are overall safe to use, but consult your health professional before deciding to take one of these PDE5 inhibitor drugs.