Time it takes to start working: You can see the results after 30-45 minutes post intaking the pill.
- This medicine can counteract PDE-5 enzyme, which is Type-5 of Phosphodiesterase enzyme that hinders mechanism of penile erection by undermining cyclic Guanosine Monophosphate (cGMP).
- Sildalis through Sildenafil and Tadalafil counteracts PDE-5 (without affecting other Phosphodiesterase types). This prevents degradation of cGMP level, which is essential for normal penile erection mechanism.
- Cyclic Guanosine Monophosphate responds to Nitric Oxide (NO) release and relaxes muscles in the penile area. It also simultaneously dilates crucial penile blood vessels such as dorsal arteries, helicine arteries, etc., in order to allow unobstructed blood flow into the reproductive organ.
- Enhanced blood supply to the organ results in hyperaemic engorgement of the reproductive organ rendering it suitable for intercourse.
Effect lasting: The effects of drug last for around four to six hours.