Time it takes to start working: Effect can be experienced within 20 to 30 minutes after consuming the pill.
- Apcalis Oral Jelly has its effects on two significant enzymes known as cGMP and PDE5 which are important for appropriate erection.
- Nitric Oxide, which is released due to sexual stimulation, catalyses cGMP in corpora cavernosa as well as in blood vessels in the male reproductive organ.
- The cGMP then allows the blood to flow into corpora cavernosa which in turn stimulates erectile tissues causing the organ to achieve erection.
- After sufficient male organ stimulation is obtained, the veins get compressed which decreases the blood flow resulting in maintenance or persistence of erection.
- The effect then ceases after copulation when the PDE5 enzyme degrades cGMP.
Effect lasting: The effect of Apcalis Oral Jelly lasts for approximately 36 hours.